The number of jobs in London being posted on job site Indeed this year has fallen by 50%, compared with 42% across the UK as a whole.
Madrid suffered the second largest fall in job adverts (46%), followed by 40% in Paris, 35% in Rome and 17% in Berlin.
The decline in vacancies in each city was much larger than the decline in each respective country.
Job postings were down by 39% in Spain, 24% in France, 24% in Italy and 17% in Berlin.
Indeed said the drop in vacancies is especially severe in face-to-face service jobs, such as food preparation and service, beauty and wellness, and hospitality and tourism.
An Indeed spokesman said: “The explosive growth of working from home in the capital cities appears to be playing a role in the hit to customer-facing jobs. In all five, the share of job postings that mention working from home is substantially higher than in the rest of the country. The main reason is the high share of postings in sectors like finance, tech and research in which work can often be done from home.
“This shift is bad news for jobs at city-centre retailers, restaurants and entertainment establishments. The drop in city centre footfall associated with remote work translates into sharp falls in business. In addition, a coronavirus-related collapse of tourism and business travel is undoubtedly also depressing hiring in those sectors.”